Risk Indicators of Sarcoidosis Evolution-Unified Protocol (RISE-UP)

Risk Indicators of Sarcoidosis Evolution-Unified Protocol (RISE-UP)

Status: Recruiting

Conditions: Sarcoidosis

Location:

University of Maryland
University of Texas Southwestern

City/State:

Baltimore, Maryland


Dallas, Texas

Contact Information:

Laura Koth
4155144369
[email protected]


Jessica Cardenas
[email protected]

Brief Summary:
The purpose of this study is to develop prediction models that can prognosticate patients with sarcoidosis using clinical data and blood markers that can be obtained during a clinic visit.
Detailed Description:

The purpose of this study is to develop prediction models that can prognosticate patients with sarcoidosis using clinical data and biological markers that can be obtained during a clinic visit.

Primary Aim/Objective The primary objective of this study is to determine which clinical features measured during a routine clinic visit are risk factors for progression of pulmonary sarcoidosis over the follow-up period in adults with pulmonary sarcoidosis.

Secondary Aim/Objectives The secondary objective is to determine if blood biomarkers measured during a routine clinic visit can improve the risk assessment for progression of pulmonary sarcoidosis over the follow-up period.

The investigators will measure two types of blood markers to achieve this goal:

  • Clinically available blood markers that are available in most clinical labs
  • Blood proteins and gene expression that reflect interferon inflammation and are not currently available as tests in clinical labs

 

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